I'm still debating who my new-gen starter will be. Much as I like Fennekin, there's no way I'm tearing myself away from Charmander, and two Fire starters would be pretty darn redundant... So, I like Froakie's design better than Chespin's, but water types are common as dirt in the late-game. Decisions, decisions...
Psystrike negates the need for an exploding Mewtwo, so I plan to arm him with that to combat any hit sponges. To take advantage of the Fighting stat in his Mega Evolution, he'll get at least one Fighting move, he'll keep mostly Psychic type moves, but I'd like to arm him with something to counteract his lousy defense.
Mewtwo's glass cannon status was such a pain back in the day. He could dish it out, but when faced with the right opponent, he certainly couldn't take it.
Mewtwo already learns Aura Sphere, awesome Fighting move, but it's a special attack. Since Mega Mewtwo X boosts physical attack, maybe there will be something else to play with...
And yeah, I do miss the R/B/Y days when Mewtwo was a veritable special wall on top of being the most deadly attacker (and this was the time when most non-Normal physical attackers lacked reliable STAB moves). My, how things have changed... Zapdos suffered the "switch to glass cannon" fate a lot worse than Mewtwo did, at least IMHO.
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